Cambridge Phenotyping presents a new fully automated AI-driven home-cage system for cognitive and behavioural phenotyping in mice. The system incorporates spontaneous alternation T-maze, novel-object recognition and object-in-place recognition tests combined with monitoring of an animal position, water consumption, quiescence and locomotion patterns, all carried out continuously and simultaneously in an unsupervised fashion over long periods of time. Mice learnt the tasks rapidly without any need for water or food restrictions.
uncovering the earliest signs of Alzheimer’s disease
The entorhinal cortex and hippocampus, regions in the brain’s medial temporal lobe, are the first to exhibit neurodegeneration in Alzheimer’s. Work pioneered by Nobel Laureate Prof John O’Keefe (UK DRI Associate Member at UCL) has identified that neurons in these...
